EP-1268: Dosimetric parameters predict toxicity in chemoradiotherapy with nelfinavir for pancreatic cancer
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منابع مشابه
Association Between Bone Marrow Dosimetric Parameters and Acute Hematologic Toxicity in Cervical Cancer Patients Undergoing Concurrent Chemoradiotherapy
OBJECTIVE We compare different dosimetric parameters in cervical cancer patients receiving concurrent chemotherapy and three-dimensional conformal radiotherapy (3DCRT) or intensity-modulated radiation therapy (IMRT) and explore the incidence of hematological toxicity (HT) in these patients. METHODS Twenty patients receiving 3DCRT or IMRT and 4 weekly doses of cisplatin (25 mg/m/w) were studie...
متن کاملCan dosimetric parameters predict acute hematologic toxicity in rectal cancer patients treated with intensity-modulated pelvic radiotherapy?
BACKGROUND To identify dosimetric parameters associated with acute hematologic toxicity (HT) in rectal cancer patients undergoing concurrent chemotherapy and intensity-modulated pelvic radiotherapy. METHODS Ninety-three rectal cancer patients receiving concurrent capecitabine and pelvic intensity-modulated radiation therapy (IMRT) were analyzed. Pelvic bone marrow (PBM) was contoured for each...
متن کاملThoracoscopic Splanchnicectomy for Pain Control in Irresectable Pancreatic Cancer
Introduction : Severepain is a major problem in patients with unresectable pancreatic cancer. The goal of this study is to evaluate the effects of Thoracoscopic Splanchnicectomy (TS) on pain control in these patients suffering from unresectable pancreatic cancer. Methods:Between years 2000 to 2011, 20 patients suffering from unresectable pancreatic cancer underwent TS due to severe pain. They w...
متن کاملSurvival Outcomes and Toxicity of Concurrent Chemoradiotherapy for Esophageal Cancer
Aims: The aim of the study was to investigate the impact of chemoradiotherapy(CRT) on survival of patients with unresectable esophageal cancer treated with radiotherapy combined with either concurrent DCF [docetaxel, cisplatin +5-fluorouracil(5-FU)] or CF [cisplatin and 5-FU).Patients and methods:Data of patients who underwent CRT for esophageal cancer during 2010 and 2015 in the department of ...
متن کاملEndowing human pancreatic ribonuclease with toxicity for cancer cells.
Onconase is an amphibian protein that is now in Phase III clinical trials as a cancer chemotherapeutic. Human pancreatic ribonuclease (RNase 1) is homologous to Onconase but is not cytotoxic. Here, ERDD RNase 1, which is the L86E/N88R/G89D/R91D variant of RNase 1, is shown to have conformational stability and ribonucleolytic activity similar to that of the wild-type enzyme but > 10(3)-fold less...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2016
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(16)32518-x